Upper Limb Spasticity in Adults

How XEOMIN Works

An abnormal hand position.

In adults with upper limb spasticity, there is an imbalance of signals from the brain to the muscles, which causes stiffness and spasms. This can lead to abnormal arm or hand positions, uncomfortable movement, and pain.1

XEOMIN® being injected.

XEOMIN is injected into muscles to help interfere with these signals. This helps decrease muscle stiffness and improve your ability to function using the affected muscles.2

A hand experiencing stiffness.

Some stiffness and spasms may still occur, but in most patients less severely.

Images are for illustration purposes only.
Individual results may vary.

XEOMIN Helps Improve Upper Limb Spasticity Symptoms

In clinical studies, XEOMIN improved muscle tone and showed functional improvements 4 weeks after initiating treatment2*

3 out of 4 patients showed at least "minimal improvement" in function with XEOMIN2*

43% of patients were rated as "much improved" (40%) or "very much improved" (3%) in function with XEOMIN2*

*Functional improvement was measured using the Global Impression of Change Scale (GICS), a global measure of a patient's functional improvement.


  1. Spasticity. American Association of Neurological Surgeons website. https://www.aans.org/en/Patients/Neurosurgical-Conditions-and-Treatments/Spasticity. Accessed June 18, 2021.
  2. XEOMIN® [Package insert]. Raleigh, NC: Merz Pharmaceuticals, LLC; 2021.