At Merz—the company behind XEOMIN—we understand the struggles and the unique needs of adult patients with upper limb spasticity. We are committed to helping you achieve a better patient experience. We recognize that you have your own unique goals and aspirations. We want to help you focus on your next adventure, next achievement, or next opportunity—not your symptoms.
In adults with upper limb spasticity there is an imbalance of signals from the brain to the muscles, which causes stiffness and spasms. This can lead to abnormal arm or hand positions, uncomfortable movement, and pain.2
XEOMIN is injected into muscles to help interfere with these signals. This helps decrease muscle stiffness and improve your ability to function using the affected muscles.1
Some stiffness and spasms may still occur, but less severely.
In clinical studies, XEOMIN significantly improved muscle tone compared with a nontherapeutic injection, known as a placebo, as measured at week 4 after initiating treatment.
The Global Impression of Change Scale (GICS) is a global measure of a patient’s functional improvement. When investigators rated how much overall change in spasticity they saw in each patient following treatment with XEOMIN1:
Read the Medication Guide before you start receiving XEOMIN® (Zeo-min) and each time XEOMIN is given to you as there may be new information. The risk information provided here is not comprehensive. To learn more:
XEOMIN is a prescription medicine used in adults:
It is not known if XEOMIN is safe and effective in children under 18 years of age.
XEOMIN may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems anytime (hours to weeks) after treatment with XEOMIN:
These symptoms can happen hours to weeks after you receive an injection of XEOMIN. These problems could make it unsafe for you to drive a car or do other dangerous activities.
Do not take XEOMIN® if you: are allergic to XEOMIN or any of the ingredients in XEOMIN (see the end of this Guide for a list of ingredients in XEOMIN), had an allergic reaction to any other botulinum toxin product such as rimabotulinumtoxinB (Myobloc®), onabotulinumtoxinA (Botox®, Botox® Cosmetic), or abobotulinumtoxinA (Dysport®) or have a skin infection at the planned injection site.
Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Talk to your doctor before you take any new medicines after you receive XEOMIN.
Using XEOMIN with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received XEOMIN in the past. Especially tell your doctor if you:
Ask your doctor if you are not sure if your medicine is one that is listed above.
Know the medicines you take. Keep a list of your medicines with you to show your doctor and pharmacist each time you get a new medicine.
XEOMIN can cause serious side effects including: See "Warnings."
The most common side effects of XEOMIN in people with chronic sialorrhea include:
The most common side effects of XEOMIN in people with upper limb spasticity include:
The most common side effects of XEOMIN in people with cervical dystonia include:
The most common side effects of XEOMIN in people with blepharospasm include:
These are not all the possible side effects of XEOMIN. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. You can ask your pharmacist or doctor for information about XEOMIN that is written for health professionals.
Active Ingredients: botulinum toxin type A
Inactive Ingredients: human albumin and sucrose
For more information, please see XEOMIN full Prescribing Information and Medication Guide.