XEOMIN Dosing Recommendations for Cervical Dystonia

In the treatment of cervical dystonia, XEOMIN® (incobotulinumtoxinA) is injected into the sternocleidomastoid, levator scapulae, splenius capitis, scalenus, and/or the trapezius muscle(s). The dose and number of injection sites in each treated muscle should be individualized based on the number and location of the muscle(s) to be treated, the degree of dystonia, muscle mass, body weight, and response to any previous botulinum toxin injections.1

Click here to download the muscle injection tracker.

hcp_2.3_Initial Dosing CD

In a placebo-controlled trial using initial XEOMIN doses of 120 and 240 units, both doses achieved greater improvement than placebo.1

  • There was no meaningful efficacy difference between the 120-unit and 240-unit treatment groups
  • The potency units for XEOMIN are specific to the preparation and are not interchangeable with other botulinum toxin products1
  • The safety and effectiveness of XEOMIN in the treatment of cervical dystonia in patients below 18 years of age have not been assessed1

hcp_2.3_Initial Dosing Unilateral Table

*Units and % of the total dose as injected during the double-blind, pivotal phase 3 study.


  1. XEOMIN® [package insert]. Raleigh, NC: Merz North America, Inc; 2015.