Adults With Upper Limb Spasticity | XEOMIN®

Adults With Upper Limb Spasticity

What's It Like Being An Adult With Upper Limb Spasticity?


  • Stroke (most common cause)
  • Traumatic brain injury
  • Multiple sclerosis
  • Spinal cord problems
    (such as lesions)
  • Cerebral palsy in adults

The majority of patients treated for upper limb spasticity with XEOMIN in clinical trials were adults with post-stroke spasticity4-6

Ruben, a patient with upper limb spasticity.

Watch Ruben's story,
an adult with upper
limb spasticity treated


  • Spasticity may be one of many possible consequences after a stroke1
  • There are a wide range of prevalence data in post–stroke spasticity, from as little as 19% to as much as 98% of patients7,8
  • The onset of spasticity after stroke is also highly variable. It may occur shortly after the stroke or more than 1 year later9
Diagnosis of Post Stroke Upper Limb Spasticity.


  • Muscle stiffness (known as hypertonia)
  • Limited range of movement
  • Reduced ability to relax muscles
  • Muscle spasms
  • Changes in limb position
  • Pain


  1. Spasticity, what is it? American Stroke Association website. Accessed November 19, 2020.
  2. Differential diagnosis for spasticity. NeuroRehab Resource website. Accessed November 19, 2020.
  3. Spasticity. American Association of Neurological Surgeons website. Accessed November 19, 2020.
  4. Elovic EP, Munin MC, Kaňovský P, Hanschmann A, Hiersemenzel R, Marciniak C. Randomized, placebo-controlled trial of incobotulinumtoxinA for upper-limb post-stroke spasticity. Muscle Nerve. 2016;53(3):415-421.
  5. Kaňovský P, Slawek J, Denes Z, et al. Efficacy and safety of botulinum neurotoxin NT 201 in poststroke upper limb spasticity. Clin Neuropharmacol. 2009;32(5):259-265.
  6. Barnes M, Schnitzler A, Medeiros L, Aguilar M, Lehnert-Batar A, Minnasch P. Efficacy and safety of NT 201 for upper limb spasticity of various etiologies—a randomized parallel-group study. Acta Neurol Scand. 2010;122(4):295-302.
  7. Wissel J, Schelosky LD, Scott J, Christe W, Faiss JH, Mueller J. Early development of spasticity following stroke: a prospective, observational trial. J Neurol. 2010;257(7):1067-1072.
  8. Ward AB. A literature review of the pathophysiology and onset of post-stroke spasticity. Eur J Neurol. 2012;19(1):21-27.